论文部分内容阅读
近日,中国农业科学院哈尔滨兽医研究所陈化兰团队研究发现,H5N1病毒确有可能通过与人流感病毒的基因重配,获得在哺乳动物之间高效空气传播的能力,从而引起人间大流行。该研究从全新角度揭示了H5N1病毒对全球公共卫生构成的现实威胁,5月3日,《科学》在线发表了相关论文,并配发了摘报评论和专题报道。同时,《自然》杂志也对此进行了报道。据了解,流感病毒基因组由8个节段的单股负链RNA分子组成,两种病毒共感染同一宿主,可发生基因分子节段的重配,理论上可以形成256种不同的基因重配病毒。历史上,禽流感病毒通过在中间宿主体内与哺乳动物流感病毒发生基因重
Recently, the Chen Hualin team from the Harbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences found that it is indeed possible that the H5N1 virus can acquire an efficient airborne transmission capability between mammals through gene reassortment with the human influenza virus, thus causing an international pandemic. The study unveiled the real threat posed by the H5N1 virus to global public health from a completely new perspective. On May 3, Science published relevant papers online and distributed snippets of commentaries and feature stories. At the same time, “Nature” magazine also reported on this. It is understood that the influenza virus genome consists of eight single-stranded negative-strand RNA molecule composition, the two viruses co-infected with the same host, gene rearrangement of gene segments occur, in theory, can form 256 different gene reassortants . Historically, avian influenza viruses have been genetically engineered to react to mammalian influenza viruses in an intermediate host