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观察干扰素α-1b灌肠治疗小儿腹泻的临床效果。选择该院2011年1月至2013年1月110例小儿腹泻患者,随机分为实验组和对照组,对照组55例患儿采用常规治疗的方法,实验组55例患儿给予干扰素α-1b灌肠治疗,分析比较两组患儿的治疗效果。实验组患儿和对照组患儿在治疗2 d后,实验组患儿的腹泻次数明显少于对照组患儿(P<0.05),具有统计学意义;实验组患儿临床症状消失、大便常规恢复正常的治疗时间明显少于对照组患儿(P<0.05),具有统计学意义;实验组患儿临床治疗总有效率96.36%,高于对照组患儿的治疗总有效率74.55%(P<0.05),具有统计学意义。在常规治疗的基础上加用干扰素α-1b灌肠治疗可以有效改善小儿腹泻患儿的临床症状,缩短治疗时间,具有较好的安全性和稳定性,副作用小,值得临床推广使用。
To observe the clinical efficacy of interferon α-1b enema in treating infantile diarrhea. A total of 110 infantile diarrhea patients from January 2011 to January 2013 in our hospital were randomly divided into experimental group and control group. 55 children in control group were treated by conventional therapy. 55 children in experimental group were treated with interferon alpha- 1b enema treatment, analysis and treatment of children in both groups. The number of diarrhea in experimental group was significantly less than that in control group (P <0.05) after 2 days of treatment in experimental group and control group, with statistical significance. The clinical symptoms of the experimental group disappeared and stool routine The recovery time was significantly less than that in the control group (P <0.05), with statistical significance. The total effective rate of clinical treatment in children in experimental group was 96.36%, higher than that in control group (74.55%, P <0.05), with statistical significance. On the basis of conventional treatment plus interferon α-1b enema treatment can effectively improve the clinical symptoms of children with pediatric diarrhea, shorten the treatment time, with good safety and stability, side effects, it is worth promoting the use of the clinic.