论文部分内容阅读
目的评价不同无创通气模式治疗早产儿肺透明膜病患者的临床疗效。方法选取2016年2月-2017年2月在医院进行救治的早产儿肺透明膜病患儿40例,根据其治疗方法不同分为观察组和对照组各20例。其中观察组患者接受双水平气道正压通气(Bi PAP)治疗,观察组患者应用鼻塞式持续正压通气(CPAP)治疗。记录2组患者经不同方法治疗后1 h以及12 h的动脉血气情况,包括二氧化碳分压(PaCO_2)值以及氧分压(PaO_2)值。记录2组患儿经不同治疗方法治疗后的肺损伤、呼吸机相关性肺炎的发生率,并统计2组治愈率。结果 2组患儿在经不同方法治疗后,观察组患儿治疗1 h、12 h后的氧分压高于对照组,二氧化碳分压低于对照组,差异均有统计学意义(P<0.05)。2组患儿经不同治疗方法治疗后,观察组患儿肺损伤及呼吸机相关性肺炎的发生率均显著低于对照组,治愈率显著高于对照组,差异均有统计学意义(P<0.05)。结论应用双水平气道正压通气治疗早产儿肺透明膜病患者可显著提升患者的治愈率,有较高的临床应用价值。
Objective To evaluate the clinical efficacy of different non-invasive ventilation modalities in the treatment of premature infants with hyaline membrane disease. Methods Forty children with hyaline membrane disease who were treated in hospital from February 2016 to February 2017 were divided into observation group (20 cases) and control group (20 cases) according to the treatment method. Patients in the observation group received bi-level positive airway pressure (Bi PAP) and patients in the observation group received nasal continuous positive airway pressure (CPAP). Arterial blood gas concentrations, including PaCO 2 and PaO 2, at 1 h and 12 h after treatment in two groups were recorded. The incidence of lung injury and ventilator-associated pneumonia in two groups of children treated by different treatment methods were recorded, and the cure rate of two groups was calculated. Results After treatment by different methods, the partial pressure of oxygen in observation group was higher than that in control group at 1 h and 12 h after treatment, and the partial pressure of carbon dioxide was lower than that in control group (P <0.05) . The incidence of lung injury and ventilator-associated pneumonia in the observation group was significantly lower than that of the control group after treatment by two groups of children with different treatment methods, the cure rate was significantly higher than that of the control group (P < 0.05). Conclusion The application of bi-level positive airway pressure ventilation in patients with hyaline membrane disease in preterm children can significantly improve the cure rate of patients with high clinical value.