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目的:分析探讨放射治疗在胃癌治疗中的作用,为临床治疗方案的选择提供科学依据。方法:对我院2010年1月~2013年8月间收治胃癌并行根治术的患者84例行术中放射治疗,并与2007年2月~2009年12月间我院行单纯胃癌手术治疗患者84例作对比,比较两组患者间不良反应、五年生存率、复发率差异。结果:I、IV期胃癌手术+放疗组患者五年生存率、复发率与单纯手术组相比差异无统计学意义(P>0.05),而II期和III期患者术中加行放射治疗组患者五年生存率明显提升、复发率降低,两组间差异显著,具有统计学意义(P<0.05)。另外,统计不良反应后可发现,本组研究中继发胃肠道不适者3例,予对症治疗后好转,无胰腺炎、吻合口瘘等严重并发症的发生。结论:胃癌根治术中加行放射治疗能显著提高II、III期胃癌患者生存率,避免术后复发,且安全可靠,不良反应少,值得临床推广。
Objective: To analyze the role of radiotherapy in the treatment of gastric cancer and provide a scientific basis for the selection of clinical treatment options. Methods: Totally 84 patients undergoing radical gastrectomy in our hospital from January 2010 to August 2013 were treated with intraoperative radiotherapy, and were treated with simple gastric cancer surgery in our hospital from February 2007 to December 2009 84 cases for comparison, two groups of patients were compared adverse reactions, five-year survival rate, recurrence rate differences. Results: There was no significant difference in the five-year survival rate and recurrence rate between patients in stage I and IV gastric cancer surgery + radiotherapy group and in surgery group (P> 0.05), while those in stage II and III patients were treated with radiotherapy The five-year survival rate of patients significantly improved, the recurrence rate decreased, the difference was significant between the two groups, with statistical significance (P <0.05). In addition, the statistical adverse reactions can be found in this group of secondary gastrointestinal discomfort in 3 cases, to improve after symptomatic treatment, no pancreatitis, anastomotic leakage and other serious complications. Conclusions: Radiotherapy combined with radiotherapy can significantly improve the survival rate of patients with stage II and III gastric cancer, avoid recurrence after operation, and is safe and reliable with few adverse reactions. It is worthy of clinical promotion.