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采用放射免疫法检测１８０例乳腺疾病患者血清ＣＡ１５－３水平，其中乳腺良性疾病４２例，乳腺癌术前５１例，乳腺癌术后无复发转移者７３例，乳腺癌术后有复发或转移者１４例。ＣＡ１５－３阳性率分别为９．５％、２７．５％、５．５％、８５．７％。结果显示，乳腺癌术后有复发或转移者的阳性率明显高于无复发转移者（Ｐ＜０．０１）。血清ＣＡ１５－３检测对乳腺癌术前诊断意义不大，而对乳腺癌术后复发和转移的监测有重要价值。
Radioimmunoassay was used to detect serum CA15-3 levels in 180 patients with breast diseases, including 42 cases of benign breast disease, 51 cases of breast cancer before surgery, 73 cases of breast cancer without recurrence and metastasis, and recurrence or metastasis after breast cancer surgery. 14 cases. The positive rate of CA15-3 was 9.5%, 27.5%, 5.5%, and 85.7%, respectively. The results showed that the positive rate of breast cancer after recurrence or metastasis was significantly higher than those without recurrence (P<0.01). The detection of serum CA15-3 has little significance in the preoperative diagnosis of breast cancer, but it is of great value in monitoring the recurrence and metastasis of breast cancer.