大肠腺瘤是重要的癌前病变,确定其恶变倾向的大小对提高大肠癌防治水平甚有帮助。r一谷氨酸转肽酶(GGT)在多种肿瘤中活性升高[‘。中又通过测定大肠正常粘膜与肿瘤组织的GGT活性,藉以探讨腺瘤中GGT活性的变化特点及其作为腺瘤恶变倾向标志及协助诊断大肠癌的价值。 材料与方法 一、标本采集 125例大肠粘膜组织中,18例为大肠癌手术标本,9例大肠非腺瘤性息肉和36例大肠腺瘤均为经结肠镜 Colorectal adenomas are important precancerous lesions, and determining the size of their malignant transformation is helpful in improving the prevention and treatment of colorectal cancer. R-glutamate transpeptidase (GGT) activity increased in various tumors [’. The GGT activity of normal mucosa and tumor tissue in the large intestine was measured to investigate the changes in GGT activity in adenomas and its value as a marker of malignant tumors in adenomas and in the diagnosis of colorectal cancer. Materials and Methods 1. Specimen collection In 125 cases of colorectal mucosal tissue, 18 cases of colorectal cancer surgery specimens, 9 cases of non-adenomas of colorectal polyps and 36 cases of colorectal adenomas were colonoscopy