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在浆细胞病中,孤立性骨髓瘤较罕见,约<5%。由于孤立性与多发性骨髓瘤(MM)两者关系仍未明,故作者对本病114例与已确诊的70例 MM 进行比较。本组男性占72%,女性28%,平均年龄51±13岁,随访时间从数周至24年。诊断标准为:①放射检查呈单个骨损害;②活检示浆细胞;③骨髓检查中骨髓瘤细胞缺如;④无贫血、高钙血症或肾脏浸润;⑤血清及/或尿中无单克隆成分;⑥免疫球强自正常或低水平。临床上均有不同程度的疼痛,由骨波及至软组织或神经根。骨损害分布,脊柱占53.5%,外周骨占46.5%,仅47例有 X 线证据,其中骨质硬化4%,溶骨损害96%。治疗方法,大多(95例)采取外科+放疗,部
In plasma cell disease, isolated myeloma is rare, about <5%. Since the relationship between solitary and multiple myeloma (MM) remains unclear, the authors compared 114 patients with this disease with 70 diagnosed MM. This group of men accounted for 72%, 28% of women, mean age 51 ± 13 years, followed up from a few weeks to 24 years. Diagnostic criteria: ① radiographic examination showed a single bone damage; ② biopsy showed plasma cells; ③ bone marrow myeloma cell absence; ④ no anemia, hypercalcemia or renal infiltration; ⑤ serum and / or no monoclonal Ingredients; ⑥ strong or low immunoglobulin level. Clinically have varying degrees of pain, from the bone to the soft tissue or nerve root. Distribution of bone lesions, spinal column accounted for 53.5%, 46.5% of peripheral bone, only 47 cases of X-ray evidence, including 4% of bone sclerosis, osteolytic lesions 96%. Treatment methods, most (95 cases) to take surgery + radiotherapy, Department