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目的探讨孤独症患儿的食物不耐受情况及忌食不耐受食物的治疗效果。方法选取孤独症患儿82例为孤独症组,健康儿童20例为健康对照组,采用酶联免疫吸附法(ELISA)检测二组血清14种食物过敏原IgG水平,并加以比较,对食物过敏原结果阳性的患儿忌食不耐受食物。结果孤独症组食物过敏原特异性IgG抗体水平显著高于健康对照组(P<0.05),忌食不耐受食物后,孤独症组患儿症状较治疗前好转,治疗前后比较差异有统计学意义(P<0.05)。结论食物过敏原特异性IgG抗体测定有助于及早发现孤独症患儿的食物不耐受,忌食不耐受食物对治疗孤独症有一定意义。
Objective To investigate the food intolerance in children with autism and the therapeutic effect of not eating food intolerant. Methods 82 children with autism were selected as autism group and 20 healthy children as healthy control group. The levels of IgG in 14 food allergens were detected by enzyme-linked immunosorbent assay (ELISA) Children with positive results should not eat intolerant food. Results The levels of specific allergen-specific IgG antibodies in autism group were significantly higher than those in healthy control group (P <0.05). After eating too much food, the symptoms in children with autism were better than those before treatment, and the differences were statistically significant before and after treatment Significance (P <0.05). Conclusion The determination of food allergen-specific IgG antibodies can help detect the early onset of food intolerance in children with autism. Tolerant to food intolerance has some significance for the treatment of autism.