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目的观察2型糖尿病患者血清脂蛋白(a)水平及其与糖尿病并发冠心病的关系。方法选择健康对照者40例,2型糖尿病患者100例(分为单纯糖尿病组50例、糖尿病并发冠心病组50例),统计相关资料及测定Lp(a)浓度。结果单纯糖尿病组血清Lp(a)浓度明显高于健康对照组,而糖尿病并发冠心病组Lp(a)浓度又明显高于单纯糖尿病组。结论 Lp(a)与糖尿病并发冠心病密切相关,可能是其发生发展的一个独立危险因素。
Objective To investigate the relationship between serum lipoprotein (a) level and type 2 diabetic patients with coronary heart disease. Methods Forty patients with healthy controls, 100 patients with type 2 diabetes mellitus (divided into simple diabetic group and 50 diabetic patients with coronary heart disease group) were selected according to statistics data and Lp (a) concentration. Results Serum Lp (a) concentration in simple diabetic group was significantly higher than that in healthy control group, while Lp (a) concentration in diabetic complicated with coronary heart disease group was significantly higher than that in simple diabetic group. Conclusions Lp (a) is closely related to diabetes and coronary heart disease, which may be an independent risk factor for its development.