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目的:探讨经内镜胆道金属支架引流术治疗恶性胆道梗阻性黄疸的疗效和安全性。方法:42例无法行手术根治性切除的恶性胆道梗阻性黄疸患者采用内镜下胆道金属支架引流术治疗。并观察血清胆红素水平及术后并发症情况,随访患者生存期和胆道支架维持通畅时间。结果:42例患者放置胆道金属支架均获成功,成功率为100.0%(42/42);术后2周内血清胆红素恢复正常30例(71.4%),明显减退12例(28.6%);2例(4.8%)发生胆管炎,3例(7.1%)发生急性轻型胰腺炎;平均支架维持通畅时间为9.6个月;6个月和1年生存率分别为64.3%(27/42)和19.0%(8/42)。结论:经内镜胆道金属支架引流术治疗恶性胆道梗阻性黄疸疗效较好,并发症少。
Objective: To investigate the efficacy and safety of endoscopic biliary metal stent drainage in the treatment of malignant biliary obstructive jaundice. Methods: Forty-two patients with malignant biliary obstruction jaundice who could not undergo radical resection were treated with endoscopic biliary metal stent drainage. The serum bilirubin level and postoperative complications were observed. Survival and biliary stenting were followed up. Results: The successful rate was 100.0% (42/42) in 42 patients. The bilirubin returned to normal in 30 cases (71.4%) within 2 weeks after operation, with a significant decrease in 12 cases (28.6%). ; Cholangitis occurred in 2 cases (4.8%) and acute pancreatitis in 3 cases (7.1%). The average duration of stent patency was 9.6 months. The 6-month and 1-year survival rates were 64.3% (27/42) And 19.0% (8/42) respectively. Conclusion: Endoscopic biliary metal stent drainage for the treatment of malignant biliary obstructive jaundice has good curative effect and few complications.