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目的观察比索洛尔治疗慢性充血性心力衰竭(CHF)的临床疗效。方法将57例CHF患者随机分为常规药物治疗组(27例)和比索洛尔治疗组(30例),观察两个月,比较两组治疗前后心功能(NYHA分级)、超声心动图变化情况。结果比索洛尔治疗组与常规药物治疗组相比,不仅总有效率明显提高(P<0.05),且治疗后心脏功能、LVESD、LVEDD及LVEF均有显著改善(P<0.05)。结论在常规药物治疗基础上加用比索洛尔,可显著提高CHF的治疗效果,改善CHF预后。
Objective To observe the clinical efficacy of bisoprolol in the treatment of chronic congestive heart failure (CHF). Methods Fifty-seven patients with CHF were randomly divided into two groups: conventional treatment group (27 cases) and bisoprolol treatment group (30 cases). The changes of cardiac function (NYHA classification) and echocardiography before and after treatment were compared . Results Compared with the conventional drug treatment group, bisoprolol treatment group not only improved the total effective rate (P <0.05), but also improved the cardiac function, LVESD, LVEDD and LVEF after treatment (P <0.05). Conclusion The addition of bisoprolol to conventional drug therapy can significantly improve the therapeutic effect of CHF and improve the prognosis of CHF.