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目的探究普萘洛尔治疗婴儿血管瘤的临床效果。方法选取新疆第一济困医院2012年12月—2013年12月收治的62例血管瘤患儿,随机分为治疗组和对照组,每组31例。对照组患儿予以平阳霉素联合地塞米松治疗,治疗组患儿应用普萘洛尔治疗。比较两组患儿治疗后的临床疗效及不良反应。结果治疗组患儿总有效率(96.8%)高于对照组(90.3%),差异有统计学意义(P<0.05)。治疗组患儿出现1例(3.2%)不良反应,对照组患儿出现3例(9.7%)不良反应;治疗组患儿不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论普萘洛尔治疗婴儿血管瘤的临床效果显著,不良反应少。
Objective To investigate the clinical effect of propranolol in the treatment of infantile hemangiomas. Methods Sixty-two children with hemangiomas who were admitted to the First Affiliated Hospital of Xinjiang Uygur Autonomous Region from December 2012 to December 2013 were randomly divided into treatment group and control group, with 31 cases in each group. Children in the control group were treated with pingyangmycin and dexamethasone, while those in the treatment group were treated with propranolol. The clinical efficacy and adverse reactions of the two groups were compared. Results The total effective rate (96.8%) in the treatment group was higher than that in the control group (90.3%), the difference was statistically significant (P <0.05). One case (3.2%) had adverse reactions in the treatment group and three cases (9.7%) had adverse reactions in the control group. The incidence of adverse reactions in the treatment group was lower than that in the control group (P <0.05 ). Conclusion Propranolol is effective in treating infantile hemangiomas with less adverse reactions.