论文部分内容阅读
目的:探讨注射用生长抑素治疗肝硬化合并上消化道出血的临床疗效。方法:选择自2013年12月至2015年12月该院收治的60例肝硬化合并上消化道出血患者为研究对象。根据随机数表法将患者分为对照组和观察组各30例。对照组患者在常规治疗的基础上应用垂体后叶素,观察组患者在常规治疗的基础上应用注射用生长抑素。结果:观察组患者中,在24 h内止血9例,24~48 h之间止血19例,治疗有效率为93.33%。对照组患者中,在48 h内止血5例,48~72 h之间止血16例,治疗有效率为70.00%,组间疗效存在显著差异(P<0.05)。两组患者均有部分患者出现头痛、心悸等轻度不良反应,组间无显著差异(P>0.05)。结论:注射用生长抑素治疗肝硬化合并上消化道出血的效果佳,起效迅速,不良反应少,建议应用。
Objective: To investigate the clinical efficacy of somatostatin for injection in the treatment of cirrhosis with upper gastrointestinal hemorrhage. Methods: From December 2013 to December 2015 in our hospital, 60 patients with cirrhosis and upper gastrointestinal bleeding were selected as the study subjects. Patients were divided into control group and observation group according to random number table method. Patients in the control group were given pituitrin on the basis of routine treatment, and patients in the observation group were given somatostatin for injection on the basis of conventional treatment. Results: In the observation group, there were 9 cases of hemostasis within 24 hours and 19 cases of hemostasis between 24 and 48 hours. The effective rate was 93.33%. Among the control group, there were 5 cases of hemostasis within 48 hours and 16 cases of hemostasis between 48 and 72 hours. The effective rate was 70.00%. There was significant difference between the two groups (P <0.05). Some patients in both groups had mild adverse reactions such as headache, palpitations, with no significant difference between the two groups (P> 0.05). Conclusion: Somatostatin injection for the treatment of cirrhosis combined with upper gastrointestinal bleeding with good effect, rapid onset, fewer adverse reactions, the proposed application.