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颅底肿瘤常常难以手术全切除，放射治疗是颅底肿瘤术后残留和／或复发以及全身状况不允许手术患者的主要治疗手段。常规分割放射治疗因受放射剂量的限制而治疗效果不理想；γ－刀、Ｘ－刀治疗较小体积（≤３ｃｍ）的颅底肿瘤时能精确聚焦照射毁损病灶而周围组织接受的剂量很少，达到类似于手术一次切除的效果。立体定向放射治疗更符合临床放射生物学的要求，而且降低了邻近颅底肿瘤的颅神经损伤率；适形调强放射治疗通过满足形状适形和放射剂量适形的要求，进一步提高了颅底肿瘤局部控制率、患者生存率以及安全性。此外，由于新的医用放射源如质子、中子、α－粒子和负Л介子等的不断涌现，颅底肿瘤放射治疗作用将更大、毒副作用更低。
Skull base tumors are often difficult to remove the total surgery, radiation therapy is residual and / or recurrence of skull base tumor surgery and general condition does not allow surgery in patients with the main treatment. Radiotherapy due to conventional radiation dose limits and the treatment effect is not satisfactory; γ-knife, X-knife treatment of smaller volume (≤ 3cm) of the skull base tumor can accurately focus the irradiation lesions and the surrounding tissue to accept a small dose , To achieve a resection effect similar to a surgery. Stereotactic radiotherapy is more in line with the requirements of clinical radiobiology, and reduce the cranial nerve injury rate adjacent to the skull base tumors; conformal IMRT by conformal shape and radiation dose conformal requirements to further improve the skull base Tumor local control rate, patient survival rate and safety. In addition, due to the continuous emergence of new sources of medical radiation such as protons, neutrons, alpha-particles, and negative pions, radiotherapy for skull base tumors will have greater effects and lower toxicities and side effects.