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目的探讨脑卒中后癫痫的临床特点及发病机制。方法对585例脑卒中患者中39例继发性癫痫患者的临床资料进行回顾性分析。结果脑卒中后癫痫的发生率为6.67%(39/585),卒中后早期癫痫的发生率为69.2%(27/39),晚期发生率为30.7%(12/39),以部分发作为最多占66.66%(26/39),卒中后癫痫的发生率与病灶部位有关,皮质病灶较易发生卒中后癫痫,皮质与皮质下比较差异有统计学意义(P<0.05),而不同卒中类型癫痫发生率差异无统计学意义(P>0.05)。结论脑卒中是老年人癫痫发作的最常见原因,皮质病灶较易发生癫痫。
Objective To investigate the clinical features and pathogenesis of post-stroke epilepsy. Methods The clinical data of 39 cases of secondary epilepsy in 585 stroke patients were analyzed retrospectively. Results The incidence of epilepsy after stroke was 6.67% (39/585), the incidence of early epilepsy after stroke was 69.2% (27/39), and the late onset rate was 30.7% (12/39), with partial seizures as the most Accounting for 66.66% (26/39). The incidence of post-stroke epilepsy was related to the location of the lesion. The incidence of post-stroke epilepsy was more likely in cortical lesions than that in the cortical and subcortical regions (P <0.05) The difference was not statistically significant (P> 0.05). Conclusion Stroke is the most common cause of epileptic seizures in the elderly. Cortical lesions are more prone to epilepsy.