人体血清总甲状腺素(T_4)的测定,可作为甲状腺功能诊断的一项重要指标。目前临床医学上常采用放射免疫法测定T_4,易造成放射性污染。本文以合成的新的具蛋白结合位点较多的载体膜材料固定T_4抗体,以晶体氯电极作原电极研制成T_4免疫电极,采用种载体膜,显著改善了非标记免疫电极的灵敏度。将此电极用于血清中T_4测量,取得了良好的结果。 Human serum total thyroxine (T_4) determination, can be used as an important indicator of thyroid function diagnosis. Currently used in clinical medicine radioimmunoassay T_4, easily lead to radioactive contamination. In this paper, T_4 antibody was immobilized on a new carrier membrane material with a large number of protein binding sites. T_4 antibody was prepared by using the crystal chlorine electrode as the original electrode, and the carrier membrane was used to significantly improve the sensitivity of the non-labeled immunodetector. The electrode was used in serum T_4 measurement, and achieved good results.