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目的 观察后程加速超分割放射治疗食管癌的临床疗效。方法 将３０ 例中段食管鳞癌患者随机分为常规放疗组（ Ａ 组） 和后程加速超分割组（ Ｂ 组） ，各１５ 例，均用６０ Ｃｏγ射线照射。 Ａ 组照射２ Ｇ Ｙ／ 次，５ 次／ 周，总量为６８ Ｇ Ｙ／６ ～７ 周。 Ｂ 组前４ 周照射同 Ａ 组，第５ 周开始１ ．５ Ｇ Ｙ／ 次，２ 次／ 日，间隔６ 小时，总量为６８ Ｇ Ｙ／５ ～６ 周。结果 局控率： Ａ 组９３ ．３ ％ （１４／１５） ， Ｂ 组９３ ．３ ％ （１４／１５） ；两组１ 、２ 、３ 年生存率分别为３３ ．３３ ％ （５／１５） 、０（０／１５） 、０（０／１５） 和８０ ％ （１３／１５） 、４６ ．６６ ％ （７／１５） 、１３ ．３３ ％（２／１５） 。结论 后程加速超分割放疗优于常规放疗。
Objective To observe the clinical efficacy of late-course accelerated hyperfractionated radiotherapy for esophageal cancer. METHODS: Thirty patients with esophageal squamous cell carcinoma were randomly divided into conventional radiotherapy group (group A) and late-course accelerated hyperfractionation group (group B). Each group was treated with 60 Co gamma rays. Group A irradiated 2 G Y/times 5 times per week for a total of 68 G Y/6 to 7 weeks. The first 4 weeks in group B irradiated with group A, and the fifth week began 1. 5 G Y/times, 2 times/day, 6 hours apart, for a total of 68 G Y/5 to 6 weeks. Results Bureau control rate: Group A 93. 3% (14/15), Group B 93. 3% (14/15); The survival rates of the two groups at 1, 2, and 3 years were 33. 33% (5/15), 0 (0/15), 0 (0/15) and 80% (13/15), 46. 66% (7/15), 13. 33% (2/15). Conclusion Late course accelerated hyperfractionated radiotherapy is superior to conventional radiotherapy.