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目的 观察后程加速超分割放射治疗食管癌的临床疗效。方法 将30 例中段食管鳞癌患者随机分为常规放疗组( A 组) 和后程加速超分割组( B 组) ,各15 例,均用60 Coγ射线照射。 A 组照射2 G Y/ 次,5 次/ 周,总量为68 G Y/6 ~7 周。 B 组前4 周照射同 A 组,第5 周开始1 .5 G Y/ 次,2 次/ 日,间隔6 小时,总量为68 G Y/5 ~6 周。结果 局控率: A 组93 .3 % (14/15) , B 组93 .3 % (14/15) ;两组1 、2 、3 年生存率分别为33 .33 % (5/15) 、0(0/15) 、0(0/15) 和80 % (13/15) 、46 .66 % (7/15) 、13 .33 %(2/15) 。结论 后程加速超分割放疗优于常规放疗。
Objective To observe the clinical efficacy of late-course accelerated hyperfractionated radiotherapy for esophageal cancer. METHODS: Thirty patients with esophageal squamous cell carcinoma were randomly divided into conventional radiotherapy group (group A) and late-course accelerated hyperfractionation group (group B). Each group was treated with 60 Co gamma rays. Group A irradiated 2 G Y/times 5 times per week for a total of 68 G Y/6 to 7 weeks. The first 4 weeks in group B irradiated with group A, and the fifth week began 1. 5 G Y/times, 2 times/day, 6 hours apart, for a total of 68 G Y/5 to 6 weeks. Results Bureau control rate: Group A 93. 3% (14/15), Group B 93. 3% (14/15); The survival rates of the two groups at 1, 2, and 3 years were 33. 33% (5/15), 0 (0/15), 0 (0/15) and 80% (13/15), 46. 66% (7/15), 13. 33% (2/15). Conclusion Late course accelerated hyperfractionated radiotherapy is superior to conventional radiotherapy.