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目的 :探讨葛根提取物对Bel-740 2人肝癌细胞的作用。方法 :实验组Bel-740 2人肝癌细胞用葛根提取物处理 ,对照组用培养液处理 ,观察并对照两组AFP ,γ -GT ,ALD ,TAT ,OCT ,ALP的分泌量。结果 :治疗组AFP分泌量、γ -GT和ALD活力明显低于对照组 (P <0 .0 5 ) ,而OCT ,TAT和ALP的活力则明显高于对照组 (P <0 .0 5 ) ,差异均具有显著性。结论 :葛根提取物能有效诱导Bel-740 2人肝癌细胞的分化。
Objective: To investigate the effect of Pueraria lobata extract on Bel-740 human hepatoma cells. Methods: The experimental group Bel-740 2 human hepatocellular carcinoma cells treated with Pueraria lobata extract, the control group treated with culture medium, the two groups of AFP, γ-GT, ALD, TAT, OCT, ALP secretion were observed and compared. Results: The secretion of AFP, the activity of γ-GT and ALD in the treatment group were significantly lower than those in the control group (P <0.05), but the activities of OCT, TAT and ALP were significantly higher than those in the control group (P0.05) , The differences were significant. Conclusion: Pueraria lobata extract can effectively induce Bel-740 human hepatoma cell differentiation.