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目的分析2011—2016年咸阳市HIV抗体检测情况及复检阳性样本的确证检测结果,为艾滋病防控提供依据。方法依照《全国艾滋病检测技术规范》(2009年版、2015年版)对1 191份筛查阳性样本进行确证试验,对确证阳性样本进行流行病学分析。结果 2011—2016年咸阳市筛查HIV样本1 456 455份,经艾滋病确证实验室确证的HIV-1抗体阳性结果916份,阴性166份,不确定109份,复检阳性与确证阳性总体符合率为76.91%;经χ~2检验,HIV-1抗体阳性及HIV-1抗体阴性例数在复检阳性数中所占比例差异有统计学意义(χ~2=14.294,P<0.05;χ~2=21.560,P<0.01),HIV-1抗体阳性检出率呈明显的线性增长趋势,拟合方程为:HIV-1抗体阳性检出率=12.17×年份-24 454(r2=0.956 8,P<0.01);医疗机构送检人群阳性率占60.37%;男女性别比例为7.18∶1,青壮年(21~50岁)占64.74%;职业以农民居多;文化程度以初中较多。结论应加强综合监测和健康教育,扩大检测点,及早发现HIV潜在感染者,以控制艾滋病的传播和流行。
Objective To analyze the detection results of HIV antibody in Xianyang City from 2011 to 2016 and the confirmatory test results of the positive samples for the review and provide evidences for the prevention and control of AIDS. Methods According to the “National AIDS Testing Technical Specification” (2009 edition, 2015 edition), 1 191 screening positive samples were confirmed and the positive samples were confirmed by epidemiological analysis. Results A total of 1 456 455 HIV samples were screened in Xianyang City from 2011 to 2016. HIV-1 antibody positive results confirmed by AIDS confirmed laboratory were 916, 166 negative and 109 uncertain. The overall coincidence rate of retest positive and confirmed positive (Χ ~ 2 = 14.294, P <0.05); χ ~ 2 test showed that there was significant difference between the positive number of HIV-1 antibody and the negative number of HIV- 2 = 21.560, P <0.01). The positive detection rate of HIV-1 antibody showed a significant linear increase trend. The fitting equation was: HIV-1 antibody positive detection rate was 12.17 × year -24 454 (r2 = 0.956 8, P <0.01). The positive rate of the medical institutions was 60.37%. The male-female ratio was 7.18:1, and the young adults (21-50 years old) accounted for 64.74%. The occupations were mostly peasants, and there were more junior high school students. Conclusion Comprehensive monitoring and health education should be strengthened, detection points should be expanded, and potential HIV infected persons should be detected as soon as possible so as to control the spread and spread of AIDS.