论文部分内容阅读
采用改良K-B法对我院430例普通血培养阳性新生儿败血症患者进行药敏试验,结果430例新生儿败血症病原菌中金黄色葡萄球菌占41.39％,表皮葡萄球菌占27.20%,克雷伯菌占6.27%,大肠埃希菌占6.04％等。机会菌感染率1995～1997年分别为34.28％,47.05％,57.4％。青霉素对金葡菌,表葡菌耐药率分别为94.1％,86.8％;头孢唑啉对金葡菌、表葡菌、克雷伯菌耐药率分别为35.3%,12.5％,95.2％;丁胺卡那对金葡菌,表葡菌,克雷伯菌,大肠埃希菌,鼠伤寒沙门菌耐药率分别为16.3％,8.8％,21.73%,12.0%,新生儿败血症病原菌仍以金葡菌为主,但机会菌感染有逐年增多趋势。常用青霉素、头孢类抗生素耐药率高。强调合理使用抗生素,以减少耐药菌株产生以及自身菌群失调引起机会菌感染。
Using modified KB method in our hospital 430 cases of normal blood culture positive neonatal sepsis patients susceptibility test results 430 cases of neonatal sepsis pathogenic Staphylococcus aureus accounted for 41.39%, Staphylococcus epidermidis accounted for 27.20%, Klebsiella accounted for 6.27%, Escherichia coli accounted for 6.04% and so on. The infection rate of opportunistic bacteria was 34.28%, 47.05% and 57.4% respectively from 1995 to 1997. The resistance rate of penicillin to Staphylococcus aureus and Staphylococcus epidermidis were 94.1% and 86.8%, respectively. The rates of resistance to Staphylococcus aureus, Staphylococcus epidermidis and Klebsiella were 35.3%, 12.5% and 95.2%, respectively. The resistance rates of amikacin to Staphylococcus aureus, Staphylococcus epidermidis, Klebsiella pneumoniae, Escherichia coli and Salmonella typhimurium were 16.3%, 8.8%, 21.73% and 12.0%, respectively. Staphylococcus aureus-based, but opportunistic bacterial infections have increased year by year. Common penicillin, cephalosporin antibiotic resistance rate. Emphasis on rational use of antibiotics to reduce the generation of drug-resistant strains and their own flora caused by opportunistic bacteria infection.