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为研究室内装饰材料对机体免疫功能的影响,将小鼠暴露于模拟家庭装修的室内环境,对照组置于无装饰材料的同样环境中,暴露1,2个月后,观察各项免疫指标。结果显示,装饰材料释放物未引起胸腺萎缩,即实验组和对照组胸腺系数无差异。脾脏在染毒半个月、1个月时无变化,而染毒2个月时,实验组的脾脏系数显著高于对照组。在染毒1个月时溶血素产生与对照组有显著性差异,而暴露2个月后又得到恢复。淋巴细胞酸性a-醋酸萘酯酶(ANAE)阳性率实验组在暴露1个月、2个月时均显著低于同期对照组。实验表明,建筑装饰材料释放物对细胞免疫和体液免疫功能均有一定的抑制作用,但未观察到持续性的体液免疫毒性及免疫器官的病理毒性改变
To study the effect of interior materials on immune function, mice were exposed to a simulated home interior environment, while the control group was placed in the same environment with no decorative material. After 1 and 2 months of exposure, various immune indexes were observed. The results showed that the release of decorative materials did not cause thymus atrophy, that is, the experimental group and the control group no difference in thymus. Spleen in the half a month, no change at 1 month, and 2 months after exposure, the experimental group’s spleen coefficient was significantly higher than the control group. Hemolysin was significantly different from the control group at 1 month after exposure and recovered after 2 months of exposure. Lymphocyte acidic a-naphthyl acetate esterase (ANAE) positive rate of the experimental group exposed 1 month, 2 months were significantly lower than the same period control group. Experiments show that the release of building decoration materials on cellular immunity and humoral immune function have some inhibitory effect, but no sustained humoral immune toxicity and pathological changes in immune organs were observed