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目的观察分析重症甲型H1N1流感(重症甲流)患者的临床特点,探讨该病的救治及预后。方法分析56例重症甲流患者的一般资料、临床表现、实验室检查、肺部CT、治疗及预后。结果 56例中,30～55岁38例(67.9%),有基础疾病者33例(58.9%),出现发热54例(96.4%),白细胞降低18例(32.1%),合并肺部感染56例(100%),死亡6例(10.7%)。死亡患者的平均年龄、功能异常脏器数量、须进行机械通气治疗的比例均明显高于存活者(P<0.05)。结论重症甲流患者年龄偏大,有发热症状并伴肺炎,血常规检查可有异常,年龄大、功能异常的脏器数量多的患者病死率较高;抗病毒药物、激素等的早期应用和控制原发病、氧疗、尽早使用呼吸机是降低病死率的关键。
Objective To observe and analyze the clinical features of patients with severe type A (H1N1) influenza and discuss the treatment and prognosis of the disease. Methods The general data, clinical manifestations, laboratory tests, lung CT, treatment and prognosis of 56 patients with severe A-flow were analyzed. Results Among the 56 cases, 38 (67.9%) were 30-55 years old, 33 (58.9%) had underlying diseases, 54 (96.4%) had fever, 18 (32.1%) had leukopenia and 56 Cases (100%), 6 patients died (10.7%). The average age of patients with death, the number of organs with abnormal function, and the proportion of patients who needed mechanical ventilation were significantly higher than those of survivors (P <0.05). Conclusion Severe cases of a stream of patients older, with fever and pneumonia symptoms, blood tests may have abnormalities, older, dysfunctional organ number of patients with high mortality; early use of antiviral drugs, hormones and other Control of primary disease, oxygen therapy, early use of ventilator is the key to reducing mortality.