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目的 研究血清超敏C -反应蛋白 (hs -CRP )和C -反应蛋白 (CRP)对严重急性呼吸综合征 (SARS)的诊断价值。方法 SARS病人 2 0例、细菌性肺炎病人 2 0例、健康对照 2 0例 ,血清hs -CRP和CRP采用胶乳免疫比浊法全自动定量测定。结果 hs -CRP和CRP测定结果分别为 :健康对照组 (0 6 9± 0 6 2 )mg/L和 (4 4± 0 9)mg/L、细菌性肺炎组 (10 79± 1 36 )mg/L和 (98 0± 2 8 9)mg/L、SARS组 (3 16± 3 72 )mg/L和 (11 0± 9 6 )mg/L。三组间差异均有显著意义 (P <0 0 1)。结论 SARS病人和细菌性肺炎病人早期血清hs -CRP和CRP均升高 ,但细菌性肺炎病人升高更加显著 ,比SARS组分别增加 2 4倍和 7 9倍 ,对SARS与细菌性性肺炎的鉴别诊断有重要意义
Objective To investigate the diagnostic value of serum hs-CRP and CRP in patients with severe acute respiratory syndrome (SARS). Methods 20 cases of SARS patients, 20 cases of bacterial pneumonia patients, 20 cases of healthy controls, serum hs-CRP and CRP using latex immunoassay quantitative automatic determination. Results The results of hs-CRP and CRP were respectively as follows: healthy control group (0 69 ± 0 6 2) mg / L and (4 4 ± 0 9) mg / L, bacterial pneumonia group / L and (98 0 ± 2 8 9) mg / L, SARS (3 16 ± 3 72) mg / L and (11 0 ± 9 6) mg / L, respectively. The differences among the three groups were significant (P <0.01). Conclusions Serum hs-CRP and CRP in early stage of SARS patients and bacterial pneumonia patients are increased, but the patients with bacterial pneumonia increased more significantly than those of SARS patients by 24 and 29 times, respectively. SARS and bacterial pneumonia Differential diagnosis is of great significance