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青阳参(Cynanchum otophyllum Schneid)系萝蘼科(Asclepiadaceae)植物。药用其根,性温味甘辛,有解毒、镇痉、祛风、除湿等作用。治风湿骨痛,癫癎,毒蛇、狂犬咬伤等。经植物化学分离鉴定及动物试验表明,本药品具有抗惊厥作用,其抗惊厥作用的有效成分为甾体酯甙元,其中主要为青阳参甙。从青阳参的中枢药理作用研究来看,青阳参具有抗实验性癫癎模型“点燃效应”,但其效应强度不如苯巴比妥,其作用持续时间较长,并且连续给药可见蓄积作用;与苯巴比妥和苯妥英钠同用时,可以见到协同作用。对中枢神经系统高级机能未见明显影响。
Cynanchum otophyllum Schneid is an Asclepiadaceae plant. Medicinal roots, warm and sweet, detoxification, town hall, hurricane, dehumidification and other effects. Governance rheumatism, epilepsy, snakes, rabies and other bites. The phytochemical isolation and identification and animal experiments showed that the drug has anticonvulsant effect, and its anticonvulsant active ingredient is steroidal ester, which is mainly Qingyang ginseng. Judging from the pharmacological effects of Qingyang ginseng, Qingyang ginseng has the “igniting effect” of the experimental epilepsy model, but its effect strength is not as strong as that of phenobarbital, and its duration is longer, and continuous administration can be seen to accumulate. Effects; Synergistic effects can be seen with phenobarbital and phenytoin sodium. There is no significant effect on the advanced functions of the central nervous system.