我室自1989至1998年在遗传咨询门诊中,对400对疑有遗传性疾病,流产及畸胎史的夫妇进行了细胞遗传学检查,发现22例异常染色体,并对10例夫妇一方染色体异常的孕妇进行产前诊断及子代随访观察,现报告如下。对象与方法1细胞遗传学检查:患者均为本地区无明显诱因而有流产,死胎史的夫 My room from 1989 to 1998 in the genetic counseling clinic, 400 pairs of suspected genetic diseases, miscarriage and teratogenic history of couples conducted a cytogenetic examination found that 22 cases of abnormal chromosomes, and 10 cases of one couple chromosomal abnormalities Of pregnant women for prenatal diagnosis and follow-up observation of offspring, are as follows. Subjects and methods 1 cytogenetic examination: patients are no obvious incentive in this region have abortion, history of stillbirth husband