目的通过一起大型聚餐引发霍乱暴发事件的调查分析,探索类似疫情防控重点。方法实验室检测霍乱弧菌,用描述流行病学与病例对照研究方法分析相关因素。结果疑似病例15例,带菌者35例,感染率11.3%,感染者均参加2010年10月4日寿宴,未参加者无感染。对36例细菌培养阳性的感染者和32例非感染者进行病例对照研究,结果显示进食香椒牛肉、怪味鸭的比值比OR值分别为6.60、3.08,有非常强的关联;第2轮就餐者感染率明显高于第1轮。结论该起疫情极可能是被霍乱弧菌污染的甲鱼和牛蛙,在加工过程中交叉污染了盛装食物及洗碗的用具,从而导致盛装的香椒牛肉、怪味鸭及第2轮所用餐具污染所致,提示食源性霍乱暴发疫情更应防范高危水产品在加工过程中对用具的交叉污染。 Objective To investigate and analyze the outbreak of cholera caused by a large dinner together to explore the similar prevention and control focus of epidemic situation. Methods Vibrio cholerae was detected in the laboratory, and related factors were analyzed using descriptive epidemiology and case-control studies. Results 15 cases were suspected cases and 35 cases were carriers. The infection rate was 11.3%. The infected persons all participated in the birthday feast on October 4, 2010, and those who did not participate were not infected. A case-control study of 36 cases of positive bacterial infection and 32 non-infected patients showed that there was a strong correlation between odds ratio (OR) and odds ratio (OR) of 6.60 and 3.08 Diner infection rate was significantly higher than the first round. Conclusions The onset of the outbreak is most likely to be turtle and bullfrog contaminated with Vibrio cholerae. During the process, contaminated food and dishwashing equipment were cross-contaminated, causing the contamination of pepper, peculiar duck and tableware used in round 2 As a result, it is suggested that the outbreak of food-borne cholera should prevent cross-contamination of utensils during the processing of high-risk aquatic products.