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目的：探讨血细胞计数与凝血因子联合检测对急性乙型肝炎患者病情的评估价值。方法：30例急性乙型肝炎患者作为研究组，体检健康人群30例作为对照组，两组患者均进行血细胞计数和凝血因子检测，观察和对比两组患者的检测结果。结果：研究组血细胞计数检测中的WBC、G%均明显高于对照组（P＜0.05）；凝血因子检测中的PT、TT、APTT研究组均明显低于对照组（P＜0.05）；血细胞计数中的WBC和L%与肝功能损害指标的Tbil、Dbil比较，具有较强的相关性（P＜0.05）；而凝血因子中的PT、APTT与肝功能损害指标的ALT、DBil、AST、TBil比较，均具有较强的相关性（P＜0.05）。结论：血细胞计数与凝血因子联合检测可以反映急性乙型肝炎患者肝脏的损害程度，具有较高临床价值。“,”Objective: To investigate the assessed value of blood cellcount and and clotting factors combined detection of the disease in patients with acute hepatitis B. Methods:30 patients with acute hepatitis B were set as the study group , 30 cases of physical health population were set as the control group, two patients were given blood count and clotting factors detection, the test results of two groups of patients were observed and compared. Results: WBC, G% of blood celldetection of the study group were significantly higher the control group(P<0.05); PT, TT, APTT of coagulation factor detection of the study group were significantly lower than the control group (P <0.05); WBC of blood cellcount and L%and the indicators of Tbil, Dbil of liver function compared with a strong correlation (P<0.05); while ALT clotting factor in the PT, APTT and liver damage indicators , DBil, AST, TBil comparison, al had a strong correlation (P<0.05). Conclusion: Blood cellcount and clotting factors combined detection may reflect the extent of damage the liver in patients with acute hepatitis B , with a high clinical value.