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前列腺癌(PCA)在欧美地区占男性恶性肿瘤第2位,约17%;我国PCA的发病率明显低于欧美国家,但随着我国人均寿命的延长、高热量饮食、缺乏运动等因素影响,近年来发病率不断攀升。目前筛查PCA的常规手段包括直肠指诊(DRE)、血清前列腺特异性抗原(PSA)检查和经直肠超声探查(TRUS),但确诊还有赖于病理组织学检查。1989年Hodge等首先提出TRUS引导前列腺穿刺活检术,此方法成为检测早期PCA的金标准,但研究表明该“标准”术式仍可能导致20%～30%的假阴性率[1]。本文在传统TRUS的基础上,结合结节回声和彩色血流等声像图特征,合理制定穿刺方案,观察其在提高PCA诊断率中的临床价值。
Prostate cancer (PCA) in the United States and Europe accounted for the second place of male malignancies, about 17%; the incidence of PCA in our country is significantly lower than in Europe and the United States, but with the extension of life expectancy in China, high-calorie diet, lack of exercise and other factors, In recent years, the incidence has been on the rise. The current routine screening of PCA includes digital rectal examination (DRE), serum prostate-specific antigen (PSA) and transrectal ultrasound (TRUS), but the diagnosis depends on histopathology. In 1989, Hodge et al first proposed the TRUS-guided prostatic biopsy, which became the gold standard for detecting early PCA. However, studies have shown that this “standard” technique may still lead to a false negative rate of 20% -30% [1]. Based on the traditional TRUS, combined with nodular echogenic and color flow characteristics such as sonography, reasonable programming puncture, to observe its clinical value in improving the diagnostic rate of PCA.