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目的 :研究西比灵治疗脑梗塞的脑血流和血流变学变化及临床疗效。方法 :采用经颅多普勒超声 (TCD)诊断技术及血流变指标检测 ,对36例脑梗塞患者服用西比灵前后变化及临床疗效进行观察 ,并与对照组相比较。结果 :TCD显示西比灵治疗后颅内动脉血流速度明显增快 ,血流变各项指标有一定程度降低 ;神经功能评分减少值显著提高 ,生活能力明显改善 ,临床总有效率达83.33 %。结论 :西比灵能改善脑梗塞患者的脑部供血供氧、降低血粘度、改善微循环 ,保护脑组织。
OBJECTIVE: To study the cerebral blood flow and hemorheology changes and clinical effects of xibingling on cerebral infarction. Methods: Transcranial Doppler ultrasonography (TCD) and hemorrheology were used to detect the changes and clinical effects of sibirine in 36 patients with cerebral infarction. The changes were compared with the control group. Results: TCD showed that the blood flow velocity of intracranial arteries increased significantly and the indexes of hemorrheology decreased to a certain extent after treatment with xibiritine. The decrease of neurological function scores was significantly improved and the life ability improved obviously. The total clinical effective rate was 83.33% . Conclusion: Sibelium can improve cerebral blood supply and oxygen supply, reduce blood viscosity, improve microcirculation and protect brain tissue in patients with cerebral infarction.