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对LDL亚型及颗粒大小的建议根据对已发表文献全面综述,提出以下LDL亚型及颗粒浓度在CHD和卒中评估一级预防危险的临床应用和建议。建议1脂蛋白亚型,特别是sdLDL颗粒的数量或浓度与CHD事件的发生发展相关。现有的研究数据结果还不足以体现sdLDL检测在一级预防中对标准危险评估有获益。建议分类:Ⅲ(不推荐脂蛋白亚型的检测)证据权重:A
Recommendations for LDL Subtypes and Particle Size Based on a comprehensive review of published literature, the following clinical recommendations and recommendations for the prevention of primary LDL subtype and particle concentrations in CHD and stroke assessment are presented. It is suggested that the number or concentration of lipoprotein subtypes, especially sdLDL particles, correlates with the occurrence and development of CHD events. The available data do not give enough evidence of the benefits of sdLDL testing in standard risk assessment in primary prevention. Recommended Classification: Ⅲ (not recommended for the detection of lipoprotein subtypes) Weight of evidence: A.