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目的观察分析对高血压患者采用降压治疗后其24 h动态血压和心脑血管事件的发生情况。方法 82例高血压患者,其中降压治疗后有39例高血压患者称为高压组,43例血压降至正常患者称为对照组。所有患者均使用24 h动态血压监测技术监察血压,观察两组患者24 h收缩压、24 h舒张压、24 h脉压及日间、夜间情况,并记录心脑血管事件发生情况。结果高压组患者24 h收缩压、24 h舒张压、24 h脉压及日间、夜间动态血压水平高于对照组(P<0.05);高压组心脑血管事件发生27例,对照组心脑血管事件发生7例,比较差异具有统计学意义(χ2=23.6258,P=0.0001<0.05)。结论高压患者较血压正常者更容易发生心脑血管疾病,脉压是至心脑血管疾病发生的重要因素,适度降压为其合理解决方式之一。
Objective To observe and analyze the occurrence of ambulatory blood pressure and cardiovascular and cerebrovascular events at 24 hours after antihypertensive treatment in hypertensive patients. Methods 82 cases of hypertensive patients, including antihypertensive therapy after 39 cases of hypertensive patients called high pressure group, 43 cases of blood pressure decreased to normal patients known as the control group. Blood pressure was monitored by 24-hour ambulatory blood pressure monitoring in all patients. Systolic blood pressure at 24 hours, diastolic blood pressure at 24 hours, pulse pressure at 24 hours, daytime and nighttime pressure were observed in both groups. Cardiovascular and cerebrovascular events were recorded. Results The systolic blood pressure at 24 hours, diastolic blood pressure at 24 hours, pulse pressure at 24 hours, daytime and nighttime ambulatory blood pressure in high pressure group were significantly higher than those in control group (P <0.05). The incidence of cardiovascular and cerebrovascular events in high pressure group was 27 cases, There were 7 cases of vascular events, the difference was statistically significant (χ2 = 23.6258, P = 0.0001 <0.05). Conclusions Patients with hypertension are more likely to develop cardiovascular and cerebrovascular diseases than those with normal blood pressure. Pulse pressure is an important factor in the development of cardiovascular and cerebrovascular diseases. Moderate decompression is one of the reasonable solutions.