儿科各种心脏病、肺炎、毛细支气管炎、输液过多等疾病并发心力衰竭应用地高辛时,如用得不当就会中毒,甚至死亡。近10多年来通过地高辛药物动力学,毒性和疗效差异的研究,提倡口服低剂量的洋地黄化量,强调新生儿和婴儿的血药浓度调整到(?)1.7ng/ml为宜。本文重点讨论正确的掌握剂量、及对洋地黄中毒的认识与预防。 Pediatric a variety of heart disease, pneumonia, bronchiolitis, excessive infusion of fluid and other diseases complicated with heart failure when digoxin, such as improper use will be poisoned, or even death. In the recent 10 years, the study on the difference of drug kinetics, toxicity and therapeutic effect of digoxin has advocated the oral administration of low dose of digitalis and emphasized that the plasma concentration of neonates and infants should be adjusted to 1.7ng / ml. This article focuses on the right to master the dose, and the cognition and prevention of digitalis poisoning.