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本文对呼和浩特城区新生儿乙肝疫苗计划免疫效果作了评价。到１９９４年底，城区新生儿乙肝疫苗５年平均报告接种率达９３．７６％；１９９５年采用“批质量保证抽样法”调查，期望接种率达９０％；血清学调查表明，新生儿乙肝疫苗免疫成功率为９６．７７％；１～５岁组儿童（目标人群）抗－ＨＢｓ阳性率达９２．０１％，较计划免疫前５．６７％明显升高（χ２＝３２６．３６，Ｐ＜０．０１）；接种儿童较未接种的同年龄组儿童ＨＢｓＡｇ阳性率下降了５３．９９％，抗－ＨＢｃ阳性率下降了７５．３２％；流行病学效果评价表明，实施计划免疫后的目标人群乙肝发病率（８．３９／１０万）较实施前的同年龄组儿童乙肝发病率（７６．９８／１０万）下降了８９．１０％。
This article evaluates the immune effect of neonatal hepatitis B vaccine in Hohhot. By the end of 1994, the average annual coverage rate of hepatitis B vaccine in newborns in urban areas reached 93.76%; in 1995, the “Batch Quality Assurance Sampling Method” was used to investigate the vaccination rate of 90%; serological investigation showed that the newborn hepatitis B vaccine immunized The success rate was 96.77%. The positive rate of anti-HBs in children aged 1-5 years old was 92.01%, significantly higher than 5.67% before planned immunization (χ2 = 326.36, P <0 .01). The positive rate of HBsAg in vaccinated children was 53.99% lower than that in unvaccinated children of the same age, and the positive rate of anti-HBc was decreased by 75.32%. The epidemiological evaluation showed that the target population after the planned immunization The incidence of hepatitis B (8.39 / 100 000) was 89.10% lower than that of children in the same age group before implementation (76.98 / 100 000).