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目的:评价阿托伐他汀治疗混合型高脂血症的疗效和安全性。方法:40例混合型高脂血症患者进入临床观察,每日口服阿托伐他汀10mg,治疗8周。结果:混合型高脂血症患者服用阿托伐他汀10mg,治疗8周,总胆固醇由(7.8±0.9)mmol/L降至(5.6±1.2)mmol/L,LDL-C由(4.5±1.0)mmol/L降至(3.2±1.3)mmol/L,甘油三酯由(3.8±1.1)mmol/L降至(2.6±1.6)mmol/L,治疗前、后差异有统计学意义(P<0.05)。治疗过程中无出现严重不良事件。结论:阿托伐他汀能有效、安全地治疗混合型高脂血症。
Objective: To evaluate the efficacy and safety of atorvastatin in the treatment of mixed hyperlipidemia. Methods: Forty patients with mixed hyperlipidemia were included in the study. Oral daily doses of atorvastatin 10 mg were given for 8 weeks. Results: In patients with hyperlipidemia, patients were treated with atorvastatin 10 mg for 8 weeks, total cholesterol decreased from (7.8 ± 0.9) mmol / L to (5.6 ± 1.2) mmol / L, and LDL-C decreased from ) to (3.2 ± 1.3) mmol / L and (3.8 ± 1.1) mmol / L to (2.6 ± 1.6) mmol / L, respectively, with significant difference between before and after treatment (P < 0.05). No serious adverse events occurred during the course of treatment. Conclusion: Atorvastatin can effectively and safely treat mixed hyperlipidemia.