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目的总结分析颅脑损伤并发中枢性低钠血症的临床特点。方法回顾性分析我科近14年收治的1 531例颅脑损伤病人血、尿电解质、渗透压等的检测结果。结果本组10例符合抗利尿激素分泌异常综合征,其中治愈8例,死亡2例;15例颅脑损伤符合脑性耗盐综合征,治愈13例,死亡2例。结论颅脑损伤并发抗利尿激素分泌异常综合征的发病机制与治疗措施不同于脑性耗盐综合征,对其进行早期诊治能降低颅脑损伤病人的致残率和死亡率。
Objective To summarize and analyze the clinical features of brain injury associated with central hyponatremia. Methods The results of blood, urine electrolytes and osmotic pressure of 1 531 cases of traumatic brain injury in our hospital in recent 14 years were retrospectively analyzed. Results The group of 10 cases met the syndrome of anti-diuretic hormone secretion, of which 8 cases were cured and 2 died. Fifteen cases of craniocerebral injury met the brain salt-consuming syndrome, 13 cases were cured and 2 died. Conclusions The pathogenesis and treatment of craniocerebral injury complicated with antidiuretic hormone syndrome are different from that of brain salt - depleted syndrome. Early diagnosis and treatment can reduce the morbidity and mortality of patients with craniocerebral injury.