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三尖杉系我国特产树种,分布较广,民间曾用以治疗肿瘤。无产阶级文化大革命以来,我国许多地方对三尖杉属的抗癌作用,从植化,药理,临床等方面开展了协作研究。临床观察证明,从该属植物分离出的总生物硷对急性白血病有一定疗效。全国三尖杉协作组进一步从总生物硷中分离并合成有效的生物硷单体——三尖杉酯硷,高三尖杉酯硷,异三尖杉酯硷、脱氧三尖杉酯硷等四种,有计划的试用于临床。我院内科血液组于1974年9月至1975年6月,曾用三尖杉酯硷和高三尖杉酯硷混合制剂试用于急性白血病,取得了一定的临床经验。1976年8月至1977年5月又在全国协作组的统一安排下,用三尖杉酯硷(单体)治疗急性非淋巴
Cephalotaxus is a endemic species of our country, widely distributed, folk used to treat the tumor. Since the Great Proletarian Cultural Revolution, antitumor effects of Cephalotaxus in many parts of China have been studied collaboratively in terms of phytochemistry, pharmacology and clinical aspects. Clinical observations show that total alkaloids isolated from the genus have a definite effect on acute leukemia. National Cephalotaxes Collaboration Group further from the total alkaloids in the separation and synthesis of effective alkalinity monomer - harringtonic acid, homoharringtonine, homoharringtonine, deoxyharringtonine and other four Species, a trial of the trial in clinical. Our hospital internal medicine blood group from September 1974 to June 1975, had used harringtonine and homoharringtonine mixed preparation for acute leukemia, and achieved some clinical experience. From August 1976 to May 1977, under the unified arrangement of the National Collaborative Group, the use of harringtonine (monomer) in the treatment of acute non-lymphoid