肾移植术后的慢性排斥反应主要表现为肾小球滤过率渐进性下降,血肌酐缓慢上升,常伴有蛋白尿(>1.0g/24h)和高血压,症状继续加重,肾功能恶化,是移植肾丧失功能的重要原因。术后第1年开始,每年10%～15%的患者发生不可逆的移植肾功能丧失,术后5年内最终因慢性排斥反应导致移植... Chronic rejection after renal transplantation mainly manifested progressive decline in glomerular filtration rate, serum creatinine increased slowly, often accompanied by proteinuria (> 1.0g / 24h) and hypertension, the symptoms continued to worsen, worsening renal function, Is an important reason for graft loss. Beginning in the first year after operation, 10% to 15% of patients undergo irreversible loss of allograft function each year, eventually resulting in chronic allograft rejection within 5 years after transplantation.