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血管生成拟态(vasculogenic mimicry,VM)是近年来提出的一种完全不同于经典的肿瘤内皮血管生成模式的全新的肿瘤血管生成模式。VM理论是肿瘤血管生成理论的重要完善补充。本文就VM的特点、发生机制、临床意义及其在妇科肿瘤中的研究进展作一综述。
Vasculogenic mimicry (VM) is a completely new model of tumor angiogenesis that is completely different from the classic tumor angiogenesis pattern in recent years. VM theory is an important and perfect complement to tumor angiogenesis theory. This article reviews the characteristics, mechanism, clinical significance and the research progress of VM in gynecologic oncology.