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目的探讨糖尿病对老年患者发生胃食管反流(GERD)的影响。方法选取糖尿病合并GERD的老年患者(DM+GERD组)和单纯GERD老年患者(GERD组)各100例,施行食管动力检查、pH监测和胃镜检查,并进行比较。结果 DM+GERD组食管收缩波传导速度低于GERD组[(2.79±1.88)vs(4.55±2.16)cm/s,P<0.05]。两组食管炎严重程度分布相一致。结论糖尿病不是导致老年病理性酸反流发生的决定因素。
Objective To investigate the effect of diabetes on gastroesophageal reflux (GERD) in elderly patients. Methods 100 elderly patients (DM + GERD group) and GERD elderly patients (GERD group) with diabetes mellitus complicated with GERD were enrolled in this study. Esophageal motility test, pH monitoring and gastroscopy were performed and compared. Results The esophageal contraction wave velocity in DM + GERD group was lower than that in GERD group [(2.79 ± 1.88) vs (4.55 ± 2.16) cm / s, P <0.05]. Two groups of esophagitis severity distribution consistent. Conclusion Diabetes mellitus is not the determinant of the occurrence of senile pathological acid reflux.