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本研究采用豚鼠股静脉内注射四碘四氯荧光素二钠，以波长为550±20nm绿色光束照射耳蜗的方法，诱导豚鼠耳蜗血管内发生光化学反应，造成豚鼠耳蜗微循环障碍的动物模型，以复合动作电位（CAP）振幅为指标，通过给豚鼠股静脉注射复方丹参注射液，观察丹参对造模豚鼠CAP的影响。结果：实验组与对照组比较，CAP振幅相对值明显提高（P＜0．001），提示丹参有改善造模豚鼠耳蜗微循环障碍的作用。并探讨其机理。
In this study, guinea pigs were intravenously injected with tetraiodotetrafluorofluorescein disodium and irradiated with green light at a wavelength of 550±20 nm to induce a photochemical reaction in the guinea pig cochlea vessels, resulting in an animal model of cochlear microcirculation disturbance in guinea pigs. The amplitude of the compound action potential (CAP) was used as an indicator. The effects of Salvia miltiorrhiza on CAP in guinea pigs were observed by injecting compound Danshen injection into the guinea pig femoral vein. Results: Compared with the control group, the relative amplitude of CAP amplitude was significantly increased in the experimental group (P<0.001), suggesting that Salvia miltiorrhiza can improve the microcirculatory disturbance in the cochlea of model guinea pigs. And explore the mechanism.