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目的 :研究激光治疗前列腺增生症后游离 /总PSA比值用于检测PSA水平的意义。方法 :应用 830e半导体激光仪对 72例前列腺增生症患者行组织内激光凝固治疗 ,用酶联免疫法于术前 1h和术后 2 4h检测患者血清总PSA和游离PSA值 ,并计算游离 /总PSA比值。结果 :术后总PSA和游离PSA值与术前相比均有明显升高 (P <0 .0 1) ,游离 /总PSA比值术前术后无显著差异 (P >0 .0 5 )。结论 :激光治疗前列腺增生症后游离 /总PSA比值比血清总PSA值的变化更为可靠。
Objective: To study the significance of free PSA / total PSA ratio after laser treatment for detecting benign prostatic hyperplasia (PSA) level. Methods: Totally 72 patients with benign prostatic hyperplasia were treated with laser photocoagulation with 830e laser diode laser. Total serum PSA and free PSA were measured at 1h before operation and 24h after operation by enzyme-linked immunosorbent assay. Free PSA PSA ratio. Results: The postoperative total PSA and free PSA values were significantly higher than those before operation (P <0.01). There was no significant difference between the preoperative and postoperative PSA / free PSA levels (P> 0.05). Conclusion: The change of free / total PSA ratio after laser treatment of benign prostatic hyperplasia is more reliable than total serum PSA.