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目的 :用双波长等吸收点法测定复方萘替芬霜中萘替芬和酮康唑的含量。方法 :萘替芬测定在 2 83nm(肩峰处 )和 3 0 1nm(酮康唑等吸收点 )进行。酮康唑测定在 2 4 2nm(峰值 )和 2 65nm(萘替芬等吸收点 )进行。结果 :该法线性良好 ,精密度高。结论 :该法可用于复方萘替芬霜的含量测定。
OBJECTIVE: To determine the contents of naftifine and ketoconazole in compound naftifine cream by dual wavelength absorption point method. Methods: Naftifine was measured at 2383 nm (shoulder point) and at 310 nm (absorption point of ketoconazole). Ketoconazole was measured at 242nm (peak) and 225nm (naftifine and other absorption points). Results: The method is good linearity and high precision. Conclusion: This method can be used for the determination of compound naftifine cream.