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目的探讨甲氨蝶呤联合米非司酮治疗子宫疤痕妊娠的临床疗效。方法 回顾性分析2005年4月到2011年6月收治的8例子宫疤痕妊娠患者的临床资料。结果 8例经阴道超声诊断为子宫疤痕妊娠的患者,给予甲氨蝶呤联合米非司酮治疗后在超声监测下行清宫术,术中出血少。8例患者保守治疗均成功。除1例失访外,余7例均在1个月内血β-HCG恢复正常,3个月内月经恢复正常。结论甲氨蝶呤联合米非司酮治疗后再行清宫术能有效的减少子宫疤痕妊娠出血,可作为治疗子宫疤痕妊娠的主要方法。
Objective To investigate the clinical efficacy of methotrexate combined with mifepristone in the treatment of uterine scar pregnancy. Methods The clinical data of 8 patients with uterine scar pregnancy who were treated from April 2005 to June 2011 were retrospectively analyzed. Results 8 cases of transvaginal ultrasound diagnosis of uterine scar pregnancy in patients given methotrexate combined with mifepristone under ultrasound monitoring undergoing curettage, less bleeding during surgery. All 8 patients were treated conservatively. Except for one case of missed follow-up, the remaining 7 cases all returned to normal levels of blood β-HCG within 1 month, and returned to normal within 3 months. Conclusion Methotrexate combined with mifepristone curettage and curettage can effectively reduce the bleeding of uterine scar pregnancy can be used as the main method of treatment of uterine scar pregnancy.