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目的探讨影响胰腺癌患者长期生存的预后因素。方法对本院2001年10月-2011年1月资料完整的551例胰腺癌患者进行回顾性研究,进行单因素生存分析。结果研究显示,性别、年龄、是否存在肝转移、是否手术、是否进行放化疗与胰腺癌患者的长期生存相关,而肿瘤部位、吸烟、饮酒及是否病理确诊与胰腺癌患者的生存时间无关。Cox多因素分析同样显示,年龄、是否存在肝转移、是否手术、是否进行放化疗等4个指标也是胰腺癌患者能否获得长期生存的独立预后因素。结论年龄、是否手术、是否进行放化疗与胰腺癌患者的生存相关,可作为胰腺癌患者的独立预后因素。早期发现、早期治疗和进行手术治疗为主辅以放化疗的综合治疗模式,是提高胰腺癌患者生存率的关键。
Objective To investigate the prognostic factors that affect the long-term survival of patients with pancreatic cancer. Methods A retrospective study was performed on 551 pancreatic cancer patients with complete data from October 2001 to January 2011 in our hospital. Univariate survival analysis was performed. Results of the study showed that gender, age, presence or absence of liver metastases, whether surgery, whether chemotherapy and long-term survival of patients with pancreatic cancer related to tumor location, smoking, alcohol consumption and whether pathological diagnosis and pancreatic cancer patients survival time has nothing to do. Cox multivariate analysis also showed that age, presence of liver metastases, whether surgery, whether chemotherapy and other four indicators of pancreatic cancer patients also be able to obtain long-term survival independent prognostic factors. Conclusions Age, surgery, radiotherapy and chemotherapy are related to the survival of patients with pancreatic cancer, and can be used as independent prognostic factors in patients with pancreatic cancer. Early detection, early treatment and surgical treatment combined with radiotherapy and chemotherapy comprehensive treatment model, is to improve the survival rate of patients with pancreatic cancer key.