作者于1975年12月～1982年12月间对778例施行单纯乳房切除术或改良根治术但没有转移病变的病人进行了研究。随访最长91个月,平均36个月。随访期间137例病人出现复发。局部复发通过手术切除,放疗或手术加放射治疗.15例晚期病人先用化疗作首要治疗,而所有其他病人复发后的首先治疗则用内分泌治疗,绝经后病人用三苯氧胺(Tamoxifen),绝 From December 1975 to December 1982, the authors studied 778 patients who had undergone simple mastectomy or modified radical mastectomy but had no metastatic disease. Follow-up up to 91 months, an average of 36 months. During the follow-up, 137 patients relapsed. Local recurrence was performed by surgical resection, radiotherapy or surgery plus radiotherapy. 15 patients with advanced disease were treated with chemotherapy first, and all other patients were treated with endocrine therapy after relapse. Tamoxifen was used for postmenopausal patients.