临床资料患儿,男,5岁,因下前牙未萌出就诊。检查:患儿发育及营养一般,智力正常。皮肤干燥无光泽,头发稀疏、卷曲,眉毛细而少,前额突出,未发现其他全身器质性疾病。既往体健,无拔牙史。但家长述患儿自小极少出汗,其父母否认有家族病史及近亲婚配。其母上颌双侧侧切牙缺失。 Clinical data Children, male, 5 years old, because the lower anterior teeth did not erupt treatment. Check: child development and nutrition in general, mental normal. Dry and dull skin, thinning hair, curly, thin and less eyebrows, prominent forehead, no other systemic organic disease found. Past physical health, no history of tooth extraction. However, parents described children with very little sweating since childhood, and their parents denied having a family history and their relative’s marriage. The mother’s maxillary bilateral lateral incisors missing.