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目的:观察慢性阻塞性肺疾病(COPD)患者血清高敏C反应蛋白(hs-CRP)水平,探讨该病对血清hs-CRP影响。方法:入选52例COPD患者,同期入选39例正常者为对照组,测定入选人群血清hs-CRP水平。结果:COPD患者血清hs-CRP水平[(1.33±0.15)mg/dl]显著高于对照组[(0.39±0.61)mg/dl]。且急性加重期水平[(1.71±0.32)mg/dl]明显高于稳定期[(0.92±0.28)mg/dl]。两亚组均显著高于对照组。结论:hs-CRP可能参与了COPD的炎症形成过程。
Objective: To observe the serum hs-CRP level in patients with chronic obstructive pulmonary disease (COPD) and to investigate the effect of hs-CRP on serum hs-CRP. Methods: Fifty-two patients with COPD were enrolled and 39 normal subjects were selected as control group during the same period. Serum hs-CRP levels were measured in selected subjects. Results: The level of hs-CRP in patients with COPD [(1.33 ± 0.15) mg / dl] was significantly higher than that in the control group [(0.39 ± 0.61) mg / dl]. (1.71 ± 0.32) mg / dl] in acute exacerbation stage was significantly higher than that in stable stage [(0.92 ± 0.28) mg / dl]. Two subgroups were significantly higher than the control group. Conclusion: hs-CRP may be involved in the inflammatory process of COPD.