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目的分析三阴性乳腺癌患者的临床病理学特点及预后影响因素。方法 40例三阴性乳腺癌患者作为实验组,同期40例非三阴性乳腺癌患者作为对照组,就两组临床病理学特点及预后影响因素进行分析。结果实验组患者肿瘤大小分级情况,小15例(37.50%)、中21例(52.50%)、大4例(10.00%),肿瘤分期,Ⅰ级12例(30.00%)、Ⅱ级18例(45.00%)、Ⅲ级10例(25.00%);对照组患者肿瘤大小分级情况,小16例(40.00%)、中20例(50.00%)、大4例(10.00%),肿瘤分期,Ⅰ级13例(32.50%)、Ⅱ级17例(42.50%)、Ⅲ级10例(25.00%);两组患者肿瘤大小及肿瘤分期情况比较差异无统计学意义(P>0.05)。实验组患者乳腺癌复发率52.50%明显高于对照组25.00%,实验组患者5年生存率50.00%明显低于对照组77.50%,差异均有统计学意义(P<0.05)。结论三阴性乳腺癌较非三阴性乳腺癌,疾病复发率高,5年生存率低,其中淋巴结转移是影响预后的主要因素。
Objective To analyze the clinicopathological features and prognostic factors of triple negative breast cancer patients. Methods 40 cases of triple negative breast cancer patients as experimental group, the same period 40 cases of non-triple negative breast cancer patients as control group, the two groups of clinicopathological features and prognostic factors. Results There were 15 cases (37.50%) in the experimental group, 21 cases (52.50%) in the experimental group, 4 cases (10.00%) in the experimental group, 12 cases (40.00%), 20 (50.00%) were large, 4 (10.00%) were large, the tumor stage, grade Ⅰ 13 cases (32.50%), 17 cases (42.50%) in grade Ⅱ and 10 cases (25.00%) in grade Ⅲ. There was no significant difference in tumor size and tumor stage between the two groups (P> 0.05). The recurrence rate of breast cancer in experimental group was significantly higher than that in control group (52.50%), while the 5-year survival rate in experimental group was significantly lower than that in control group (50.00% vs. 77.50%, P <0.05). Conclusions Triple negative breast cancer has higher disease recurrence rate and lower 5-year survival rate than non-triple negative breast cancer. Lymph node metastasis is the main factor affecting prognosis.