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放射治疗是多年来用于治疗肺癌的有效手段之一,通过足量的放射,绝大部分病例的肿瘤能大部或基本消退,获得一定的近期疗效,有些病例还能获碍更好的远期疗效。如Smart报告一组经高度选择的肺癌病例。单纯放疗五年生存率为22.5%(9/40)。Kirch在一组经选择的鳞癌病例中得到29.5%的五年生存率。日本学者报告Ⅰ期肺癌的五年生存率在20～30%之间。然而由于肺癌的放射敏感性较低,而同时接受照射的正常肺组织的放射耐受性较差,常在放射剂量低于肿瘤致死量时已发生肺的放射反应,以及由于远处转移的问题不可能由放射来解决等原因使大多数病例不能根治,总的三年生存率在10%以下。为了提高疗效,近年来各国工作者做了许多研究工作,取得了一些进展,现分述于后。
Radiation therapy is one of the effective methods used for the treatment of lung cancer for many years. With sufficient radiation, most of the tumors in the cases can be mostly or almost subsided, obtaining a certain short-term curative effect, and some cases can also hinder a better distance. Effect. Smart reports a group of highly selected lung cancer cases. The 5-year survival rate of radiotherapy alone was 22.5% (9/40). Kirch had a 29.5% five-year survival rate in a group of selected squamous cell carcinoma cases. Japanese scholars report that the five-year survival rate of stage I lung cancer is between 20 and 30%. However, due to the low radiosensitivity of lung cancer, and the poor radioresistance of the normal lung tissue receiving irradiation at the same time, the radiation reaction of the lung has often occurred when the radiation dose is lower than the tumor lethal dose, and due to the problem of distant metastasis. It is impossible to solve by radiation and other reasons, most cases can not be cured, and the overall three-year survival rate is below 10%. In order to improve the efficacy, workers in various countries have done a lot of research work in recent years and made some progress.