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目的:探索气管内推注肺表面活性物质(PS)的最佳方法。方法:122例新生儿呼吸窘迫综合征(NRDS)患儿随机分为两组,比较不同的气管内给药方法对血氧饱和度(SaO2)、药物反流等的影响。结果:试验组在SaO2、药物反流方面好于对照组。并发症发生情况两组患儿无明显差异。结论:试验组给药方法操作简便,减轻NRDS患儿缺氧程度,减少药物反流,值得临床推广。
Objective: To explore the best method for intratracheal instillation of pulmonary surfactant (PS). Methods: A total of 122 neonates with respiratory distress syndrome (NRDS) were randomly divided into two groups. The effects of different intratracheal routes of administration on blood oxygen saturation (SaO2) and drug reflux were compared. Results: The experimental group in the SaO2, drug reflux better than the control group. The incidence of complications between the two groups no significant difference. Conclusion: The experimental group is simple and convenient to administer, which can reduce the degree of hypoxia and reduce drug reflux in children with NRDS, which is worthy of clinical promotion.